John Que
That's right. This is the Finnish Study:
The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. N Engl J Med. 1994 Apr 14;330(15):1029-35. PMID: 8127329
"Unexpectedly, we observed a higher incidence of lung cancer among the men who received beta carotene than among those who did not."
But there are also studies where an *inverse* relationship between beta carotene and lung cancer was found, so the situation is not so clear:
Connett JE, Kuller LH, Kjelsberg MO, Polk BF, Collins G, Rider A, Hulley SB. Relationship between carotenoids and cancer. The Multiple Risk Factor Intervention Trial (MRFIT) Study. Cancer. 1989 Jul 1;64(1):126-34. PMID: 2731108
"The results of this study provide further evidence for a possible protective effect of beta carotene against lung cancer among cigarette smokers."
Menkes MS, Comstock GW, Vuilleumier JP, Helsing KJ, Rider AA, Brookmeyer R. Serum beta-carotene, vitamins A and E, selenium, and the risk of lung cancer. N Engl J Med. 1986 Nov 13;315(20):1250-4. PMID: 3773937
-- Juhana
