Recommendations for a weekend in Napa and Oregon

You really do need to spend a little time on MSN Maps or Mapquest as you seem to have so little knowledge of distances in this part of the country. You will be hard-pressed to see much of San Francisco in two days, let alone accomplish much in Napa or Sonoma. Driving to Oregon or Yosemite, as the others have said, is not possible as a third stop in such a short time.

You should prioritize what you want to see and plan accordingly. If you've never been to San Francisco, I'd suggest two days there and a day in Sonoma OR Napa. If wine country is your priority, you could spend a day each in Napa and Sonoma, and catch a quick highlight of San Francisco (enough to get the flavor of the city) in one day.

Know too that most people can visit no more than maybe 5 or 6 wineries in a single day..... if they're tasting, so go to the Napa Valley and Sonoma wineries websites, or pick up a California Wine Country guide book somewhere. Plan it out realistically. Three days will just scratch the surface, but you WILL have a great time.